Mining Dan Brown's work has done rather well for Ron Howard over the years, so it was somewhat inevitable that he would tackle another tome.
Inferno finds Tom Hanks' symbologist Robert Langdon in Italy, grappling with amnesia and a chilling puzzle revolving around Dante's Inferno. He will face a new and cunning adversary and an ingenious riddle that pulls him into a landscape of classic art, secret passageways, and futuristic science. And he will need the help of doctor Sienna Brooks (Felicity Jones), who aids him in recovering his memories even as they head out on his latest quest.
This time around the danger comes in the form of a deadly virus lying at the heart of a mystery. So it is up to Langdon to become, as someone says in the trailer, humanity's final hope.
With Omar Sy (X-Men: Days Of Future Past), Ben Foster (3:10 To Yuma), Sidse Babett Knudsen (Borgen) and Irrfan Khan (Life Of Pi) in the cast, Inferno is out in the UK on 14 October.