Hill has written the script based on a story by Denis Hamill, which sees a top assassin double-crossed by gangsters and handed over to a rogue surgeon (Sigourney Weaver) who turns him into a woman. Now a hit woman, she heads out for some vengeance, aided by a nurse named Johnnie who also has secrets.
It will be an interesting role for Rodriguez to tackle and a welcome leading performance give how often she has been in ensembles recently. She is taking over the job from Freida Pinto (Slumdog Millionaire), who was attached a couple of months ago before the film made its initial rounds at the Toronto Film Festival market. Hill will start rolling the cameras next this month in Vancouver.
Rodriguez, most recently back as Letty for Fast & Furious 7, is filming family drama Milton's Secret. Weaver was part of the cast for Neill Blomkamp's (District 9) Chappie and will be seen in A Monster Calls and has a cameo in Paul Feig's (Bridesmaids) Ghostbusters, which arrives in UK cinemas on 15 July.