This time around, the focus is even more on the Agent programme that created the numerically named killing machine, genetically engineered to be stronger, faster, smarter and frankly better than us mere mortals.
His latest target is a mega-corporation that plans to unlock the secret of Agent 47's past to create an army of killers whose powers surpass even his own. Teaming up with a young woman who may hold the secret to overcoming their powerful and clandestine enemies, 47 confronts stunning revelations about his own origins and squares off in an epic battle with his deadliest foe.
With Rupert Friend (The Young Victoria) as the mysterious and deadly Agent 47, the film also features Hannah Ware (Shame), Zachary Quinto (Star Trek Into Darkness), Ciarán Hinds (Tinker Tailor Soldier Spy), Thomas Kretschmann (Wanted), Emilio Rivera (Collateral) and Dan Bakkedahl (The Heat), who you see being roundly outsmarted by Agent 47 at the start of the trailer.
Aleksander Bach is behind the camera for this one and the trailer certainly promises a lot of what you might expect from a Hitman outing with Agent 47 showing off his scientifically enhanced set of skills and lots of things going boom.
Hitman: Agent 47 sneaks into US cinemas on 21 August before heading to the UK on 28 August.