John Francis Daley and Jonathan Goldstein are making their joint directorial debut with the film, which finds the grown up Rusty Griswold (Helms) taking his wife (Applegate) and his children on a cross-country trip to replicate the one his father took years ago. The plan is to end up at Walley World. Leslie Mann (This Is 40) is set to play Rusty's sister Audrey, while Chris Hemsworth (Thor) will be her husband Stone.
Chase and D'Angelo's reprisal of their original roles is expected to be little more than a cameo appearance, but at least there is now photographic evidence that they were on set.
Keegan-Michael Key (Let's Be Cops) and Regina Hall (Scary Movie) are also among the cast as an annoyingly perfect couple the new Griswolds meet along their journey.
Vacation is currently in post-production and is out in the UK on 15 November.